Information on Kniest dysplasia
Thursday, March 20th, 2008Information on Kniest dysplasia
Kniest dysplasia and demonstrated abnormality of collagen fibril organization by electron microscopy in each. Fibrils were much thinner than normal and were irregular in shape, without the characteristic banding pattern. Furthermore, chondrocalcin was found to be absent from the extracellular matrix of epiphyseal cartilages and to be abnormally concentrated in intracellular vacuolar [...]
